"I was like, bedridden."

The Trainwreck actress opened up about her experience while speaking on The Howard Stern Show earlier this year.

"I have this gene, GDF15, which makes you extremely prone to nausea, which is why I was so sick during my pregnancy," she said.

"I tried Ozempic almost three years ago and I was like, bedridden. I was like, vomiting - and then you have no energy. But other people take it and they’re all good."

“You’re like, ‘Wait a minute. Can we slow down?’ The side effects are you have a better personality.”

“I tried it and I was vomiting and I’m in bed and my son’s like, ‘Can you play tag?’ I’m like, ‘I can’t.’ I was shrivelling,” Schumer said.

She explained that although she “lost 30 pounds so quick” and “looked great”, Ozempic was not worth it for her: “I couldn’t lift my head off the pillow, so what’s the point?”

Over the weekend, the 43-year-old opened up further about Ozempic, which is also known under the name Wegovy,

"Three years ago, I tried Wegovy.

"I was puking, I couldn’t handle it," she explained. "I don’t know if they’ve changed the formula, whatever."

She said she then spoke to a doctor about her experience and was prescribed hormones after she discovered she 'was in perimenopause'.

Schumer explained that she then tried Mounjaro, a GLP-1 drug for type 2 diabetes that is also prescribed for weightloss.

"My hair is fuller, my skin is better, I have more energy, I want to get down more...if you know what I mean. I’m talking about sex. So that’s been great and Mounjaro’s been great.

"And, look, it’s not covered by insurance unless you have diabetes or like severe obesity, which most of the internet thinks I have.

"But I’m having a really good experience with it and I wanted to keep it real with you about that."